منابع مشابه
Serious verapamil poisoning: treatment with intravenous calcium gluconate.
Verapamil is an antiarrhythmic and antianginal drug which selectively inhibits membrane transport and release of calcium from the endoplasmic reticulum, depressing the sinus node and atrioventricular conduction as well as producing a negative inotropic effect on the myocardium. Here I describe a patient who suffered the adverse haemodynamic and electrocardiographic effects consequent upon selfp...
متن کاملSuccessful management of serious disopyramide poisoning.
A case of deliberate disopyramide overdosage is described. Circulatory collapse was treated by means of a large dose of isoprenaline, and charcoal haemoperfusion was used in an attempt to enhance the elimination of disopyramide. The suitability of this treatment regime is discussed in the light of findings from animal studies and the implications for the management of the disopyramide-poisoned ...
متن کاملHyperinsulinemic euglycemia therapy for verapamil poisoning: a review.
Treatment of patients with verapamil overdose remains challenging. Traditional decontamination and supportive measures with intravenous calcium and vasopressors are the mainstays in initial care. Recently, the successful use of rescue hyperinsulinemic euglycemia therapy has been described in multiple cases. Treatment resulted in improved hemodynamic parameters and increased metabolic efficiency...
متن کاملNew treatment methods in verapamil poisoning: experimental studies.
The aim of this study was to evaluate the effectiveness of the treatment with 4-aminopyridine (4-AP, potassium channel inhibitor) and Bay K 8644 (calcium channel activator) in experimentally evoked verapamil poisoning in rats and to compare the results of this treatment with the effectiveness of widely accepted methods (adrenaline, calcium compounds). The experiment was carried out on male and ...
متن کاملVerapamil: its potential for causing serious complications in patients with hypertrophic cardiomyopathy.
Verapamil is extremely effective in the treatment of patients with hypertrophic cardiomyopathy. However, the basic physiologic actions of the drug may lead to serious adverse effects. An appreciation of this and an understanding of when these adverse effects are most likely to occur will minimize the potential of verapamil to cause serious complications in patients with hypertrophic cardiomyopa...
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ژورنال
عنوان ژورنال: BMJ
سال: 1978
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6151.1574-a